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OUR COMPOUND

PP211 — A First-in-Class Metabolic Compound

PP211 is WayPath's lead compound, a novel small molecule that exploits the unique metabolic vulnerabilities of brain tumor cells. Unlike existing therapies, PP211 is designed to cross the blood-brain barrier, selectively target tumor cell energy pathways, and work independently of glucose metabolism.

How PP211 Works

Crosses the Blood-Brain Barrier

Targets Tumor Cell Energy

Selectively Kills Tumor Cells

Works Independently of Glucose

PP211 Key Features

Once-Daily Oral

BBB Penetration Confirmed

Broad Oncology Potential

Low Toxicity Profile

Competitive Landscape — How PP211 Compares

Crosses the Blood-Brain Barrier

PP211: Confirmed ✓ | Temozolomide: Partial | Radiation Therapy: N/A | Novocure Optune: N/AIf customers can’t find it, it doesn’t exist. Clearly list and describe the services you offer. Also, be sure to showcase a premium service.

Low Systemic Toxicity

PP211: Yes ✓ | Temozolomide: No | Radiation Therapy: No | Novocure Optune: YesHaving a big sale, on-site celebrity, or other event? Be sure to announce it so everybody knows and gets excited about it.

No Hair / Weight Loss Expected

PP211: Yes ✓ | Temozolomide: No | Radiation Therapy: No | Novocure Optune: YesAre your customers raving about you on social media? Share their great stories to help turn potential customers into loyal ones.

Oral / Home Administration

PP211: Yes ✓ | Temozolomide: Yes | Radiation Therapy: No | Novocure Optune: NoRunning a holiday sale or weekly special? Definitely promote it here to get customers excited about getting a sweet deal.

Works in Treatment-Resistant Tumors

PP211: Yes ✓ | Temozolomide: No | Radiation Therapy: Limited | Novocure Optune: LimitedHave you opened a new location, redesigned your shop, or added a new product or service? Don't keep it to yourself, let folks know.

Intellectual Property & Validation

Patent: 1 — BPA Scaffold Compounds

Covers fenofibrate-derived metabolic anti-cancer compounds that inhibit mitochondrial respiration.

Patent: 2 — Benzo-Thiazole Scaffold (PP211)

PP211 is the lead compound — uniquely kills tumor cells without engaging glycolysis, providing treatment advantage across varying tumor microenvironments.

Exclusive License: LSU Health Sciences Center

WayPath holds exclusive, perpetual commercialization rights from LSU Health Sciences Center, New Orleans, for all covered compounds.

NIH STTR Grant Awarded — Competitive Federal Grant

NIH STTR Phase I grant awarded Q4 2022, validating scientific merit of PP211. Phase II application submitted Novermber 2025.

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